Ghost brought up the idea of casting. Personally, I am of the personal opinion that is my idea that the movie should be animated. At least that's what I think. Even though few people seem to admit they liked the movie, I want to use the animation style of FF: The Spirits Within. I REALLY liked that animation style that I have dubbed hyper-realistic. I like the word hyper.
I think animation should be used for several reasons. I discussed the difficulties in the power suit in an earlier post. Furthermore, Samus will be spending a lot of time in the suit. I think actors are hesitant to lose face time by being stuck behind a helmet such as that. Furthermore, the actress who is credited as doing Samus's voice for Prime and Echoes is very talented. I would love to hear her interpretation of the character beyond the grunts. Also, the environment of the story would necessitate the use of much CGI anyway for the characters and locations. While modern techniques of combining live action and CGI is very refined, having both be one or the other looks better in my opinion. I think the movie should be done in the latter.
But then again, that is just a personal opinion.