While Square-Enix has been keeping their handheld efforts centered around remakes of NES- and SNES-era and Kingdom Hearts games, a honest-to-goodness original Final Fantasy on the Nintendo DS. The game, Final Fantasy: The 4 Heroes of Light, adds a new twist to the old formula with storybook presentation, courtesy of the crew behind the well-received DS remakes of Final Fantasy III and IV.
The game is already dated for an October 5, 2010 release, with a $34.99 USD MSRP. Keep an eye on MyGamer for more details as they become available.